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A Nonhuman Primate Scrub Typhus Model: Protective Immune Responses Induced by pKarp47 DNA Vaccination in Cynomolgus Macaques

We developed an intradermal (ID) challenge cynomolgus macaque (Macaca fascicularis) model of scrub typhus, the leading cause of treatable undifferentiated febrile illness in tropical Asia, caused by the obligate intracellular bacterium, Orientia tsutsugamushi. A well-characterized animal model is re...

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Detalles Bibliográficos
Autores principales:	Paris, Daniel H., Chattopadhyay, Suchismita, Jiang, Ju, Nawtaisong, Pruksa, Lee, John S., Tan, Esterlina, Dela Cruz, Eduardo, Burgos, Jasmin, Abalos, Rodolfo, Blacksell, Stuart D., Lombardini, Eric, Turner, Gareth D., Day, Nicholas P. J., Richards, Allen L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2015
Materias:	Immunotherapy and Vaccines
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319312/ https://www.ncbi.nlm.nih.gov/pubmed/25601925 http://dx.doi.org/10.4049/jimmunol.1402244

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