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Epigenome Engineering in Cancer: Fairytale or a Realistic Path to the Clinic?
Epigenetic modifications such as histone post-transcriptional modifications, DNA methylation, and non-protein-coding RNAs organize the DNA in the nucleus of eukaryotic cells and are critical for the spatio-temporal regulation of gene expression. These epigenetic modifications are reversible and prec...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319383/ https://www.ncbi.nlm.nih.gov/pubmed/25705610 http://dx.doi.org/10.3389/fonc.2015.00022 |