Cargando…
Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol
Mycobacterium sp. strain VKM Ac-1817D is capable of converting phytosterol into 9α-hydroxy androst-4-ene-3,17-dione (9-OH-AD), which is a valuable intermediate for the steroid pharmaceutical industry. Here, a complete genome sequence of the strain is reported. The genome consists of a single circula...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319502/ https://www.ncbi.nlm.nih.gov/pubmed/25635031 http://dx.doi.org/10.1128/genomeA.01447-14 |
_version_ | 1782355969838153728 |
---|---|
author | Shtratnikova, Victoriya Y. Schelkunov, Mikhail I. Dovbnya, Dmitry V. Pekov, Yury A. Bragin, Eugeny Y. Ashapkin, Vasily V. Donova, Marina V. |
author_facet | Shtratnikova, Victoriya Y. Schelkunov, Mikhail I. Dovbnya, Dmitry V. Pekov, Yury A. Bragin, Eugeny Y. Ashapkin, Vasily V. Donova, Marina V. |
author_sort | Shtratnikova, Victoriya Y. |
collection | PubMed |
description | Mycobacterium sp. strain VKM Ac-1817D is capable of converting phytosterol into 9α-hydroxy androst-4-ene-3,17-dione (9-OH-AD), which is a valuable intermediate for the steroid pharmaceutical industry. Here, a complete genome sequence of the strain is reported. The genome consists of a single circular 6,324,222-bp chromosome with a G+C content of 66.2% and encodes approximately 6,000 CDSs, 54 tRNAs, and 6 rRNAs. |
format | Online Article Text |
id | pubmed-4319502 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | American Society for Microbiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-43195022015-02-09 Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol Shtratnikova, Victoriya Y. Schelkunov, Mikhail I. Dovbnya, Dmitry V. Pekov, Yury A. Bragin, Eugeny Y. Ashapkin, Vasily V. Donova, Marina V. Genome Announc Prokaryotes Mycobacterium sp. strain VKM Ac-1817D is capable of converting phytosterol into 9α-hydroxy androst-4-ene-3,17-dione (9-OH-AD), which is a valuable intermediate for the steroid pharmaceutical industry. Here, a complete genome sequence of the strain is reported. The genome consists of a single circular 6,324,222-bp chromosome with a G+C content of 66.2% and encodes approximately 6,000 CDSs, 54 tRNAs, and 6 rRNAs. American Society for Microbiology 2015-01-29 /pmc/articles/PMC4319502/ /pubmed/25635031 http://dx.doi.org/10.1128/genomeA.01447-14 Text en Copyright © 2015 Shtratnikova et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) . |
spellingShingle | Prokaryotes Shtratnikova, Victoriya Y. Schelkunov, Mikhail I. Dovbnya, Dmitry V. Pekov, Yury A. Bragin, Eugeny Y. Ashapkin, Vasily V. Donova, Marina V. Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol |
title | Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol |
title_full | Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol |
title_fullStr | Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol |
title_full_unstemmed | Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol |
title_short | Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol |
title_sort | complete genome sequence of mycobacterium sp. strain vkm ac-1817d, capable of producing 9α-hydroxy-androst-4-ene-3,17-dione from phytosterol |
topic | Prokaryotes |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319502/ https://www.ncbi.nlm.nih.gov/pubmed/25635031 http://dx.doi.org/10.1128/genomeA.01447-14 |
work_keys_str_mv | AT shtratnikovavictoriyay completegenomesequenceofmycobacteriumspstrainvkmac1817dcapableofproducing9ahydroxyandrost4ene317dionefromphytosterol AT schelkunovmikhaili completegenomesequenceofmycobacteriumspstrainvkmac1817dcapableofproducing9ahydroxyandrost4ene317dionefromphytosterol AT dovbnyadmitryv completegenomesequenceofmycobacteriumspstrainvkmac1817dcapableofproducing9ahydroxyandrost4ene317dionefromphytosterol AT pekovyurya completegenomesequenceofmycobacteriumspstrainvkmac1817dcapableofproducing9ahydroxyandrost4ene317dionefromphytosterol AT bragineugenyy completegenomesequenceofmycobacteriumspstrainvkmac1817dcapableofproducing9ahydroxyandrost4ene317dionefromphytosterol AT ashapkinvasilyv completegenomesequenceofmycobacteriumspstrainvkmac1817dcapableofproducing9ahydroxyandrost4ene317dionefromphytosterol AT donovamarinav completegenomesequenceofmycobacteriumspstrainvkmac1817dcapableofproducing9ahydroxyandrost4ene317dionefromphytosterol |