Cargando…

Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol

Mycobacterium sp. strain VKM Ac-1817D is capable of converting phytosterol into 9α-hydroxy androst-4-ene-3,17-dione (9-OH-AD), which is a valuable intermediate for the steroid pharmaceutical industry. Here, a complete genome sequence of the strain is reported. The genome consists of a single circula...

Descripción completa

Detalles Bibliográficos
Autores principales: Shtratnikova, Victoriya Y., Schelkunov, Mikhail I., Dovbnya, Dmitry V., Pekov, Yury A., Bragin, Eugeny Y., Ashapkin, Vasily V., Donova, Marina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319502/
https://www.ncbi.nlm.nih.gov/pubmed/25635031
http://dx.doi.org/10.1128/genomeA.01447-14
_version_ 1782355969838153728
author Shtratnikova, Victoriya Y.
Schelkunov, Mikhail I.
Dovbnya, Dmitry V.
Pekov, Yury A.
Bragin, Eugeny Y.
Ashapkin, Vasily V.
Donova, Marina V.
author_facet Shtratnikova, Victoriya Y.
Schelkunov, Mikhail I.
Dovbnya, Dmitry V.
Pekov, Yury A.
Bragin, Eugeny Y.
Ashapkin, Vasily V.
Donova, Marina V.
author_sort Shtratnikova, Victoriya Y.
collection PubMed
description Mycobacterium sp. strain VKM Ac-1817D is capable of converting phytosterol into 9α-hydroxy androst-4-ene-3,17-dione (9-OH-AD), which is a valuable intermediate for the steroid pharmaceutical industry. Here, a complete genome sequence of the strain is reported. The genome consists of a single circular 6,324,222-bp chromosome with a G+C content of 66.2% and encodes approximately 6,000 CDSs, 54 tRNAs, and 6 rRNAs.
format Online
Article
Text
id pubmed-4319502
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher American Society for Microbiology
record_format MEDLINE/PubMed
spelling pubmed-43195022015-02-09 Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol Shtratnikova, Victoriya Y. Schelkunov, Mikhail I. Dovbnya, Dmitry V. Pekov, Yury A. Bragin, Eugeny Y. Ashapkin, Vasily V. Donova, Marina V. Genome Announc Prokaryotes Mycobacterium sp. strain VKM Ac-1817D is capable of converting phytosterol into 9α-hydroxy androst-4-ene-3,17-dione (9-OH-AD), which is a valuable intermediate for the steroid pharmaceutical industry. Here, a complete genome sequence of the strain is reported. The genome consists of a single circular 6,324,222-bp chromosome with a G+C content of 66.2% and encodes approximately 6,000 CDSs, 54 tRNAs, and 6 rRNAs. American Society for Microbiology 2015-01-29 /pmc/articles/PMC4319502/ /pubmed/25635031 http://dx.doi.org/10.1128/genomeA.01447-14 Text en Copyright © 2015 Shtratnikova et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Prokaryotes
Shtratnikova, Victoriya Y.
Schelkunov, Mikhail I.
Dovbnya, Dmitry V.
Pekov, Yury A.
Bragin, Eugeny Y.
Ashapkin, Vasily V.
Donova, Marina V.
Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol
title Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol
title_full Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol
title_fullStr Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol
title_full_unstemmed Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol
title_short Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol
title_sort complete genome sequence of mycobacterium sp. strain vkm ac-1817d, capable of producing 9α-hydroxy-androst-4-ene-3,17-dione from phytosterol
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319502/
https://www.ncbi.nlm.nih.gov/pubmed/25635031
http://dx.doi.org/10.1128/genomeA.01447-14
work_keys_str_mv AT shtratnikovavictoriyay completegenomesequenceofmycobacteriumspstrainvkmac1817dcapableofproducing9ahydroxyandrost4ene317dionefromphytosterol
AT schelkunovmikhaili completegenomesequenceofmycobacteriumspstrainvkmac1817dcapableofproducing9ahydroxyandrost4ene317dionefromphytosterol
AT dovbnyadmitryv completegenomesequenceofmycobacteriumspstrainvkmac1817dcapableofproducing9ahydroxyandrost4ene317dionefromphytosterol
AT pekovyurya completegenomesequenceofmycobacteriumspstrainvkmac1817dcapableofproducing9ahydroxyandrost4ene317dionefromphytosterol
AT bragineugenyy completegenomesequenceofmycobacteriumspstrainvkmac1817dcapableofproducing9ahydroxyandrost4ene317dionefromphytosterol
AT ashapkinvasilyv completegenomesequenceofmycobacteriumspstrainvkmac1817dcapableofproducing9ahydroxyandrost4ene317dionefromphytosterol
AT donovamarinav completegenomesequenceofmycobacteriumspstrainvkmac1817dcapableofproducing9ahydroxyandrost4ene317dionefromphytosterol