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Maternal-zygotic knockout reveals a critical role of Cdx2 in the morula to blastocyst transition

The first lineage segregation in the mouse embryo generates the inner cell mass (ICM), which gives rise to the pluripotent epiblast and therefore the future embryo, and the trophectoderm (TE), which will build the placenta. The TE lineage depends on the transcription factor Cdx2. However, when Cdx2...

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Detalles Bibliográficos
Autores principales: Jedrusik, Agnieszka, Cox, Andy, Wicher, Krzysztof, Glover, David M., Zernicka-Goetz, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319684/
https://www.ncbi.nlm.nih.gov/pubmed/25512302
http://dx.doi.org/10.1016/j.ydbio.2014.12.004