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Maternal-zygotic knockout reveals a critical role of Cdx2 in the morula to blastocyst transition
The first lineage segregation in the mouse embryo generates the inner cell mass (ICM), which gives rise to the pluripotent epiblast and therefore the future embryo, and the trophectoderm (TE), which will build the placenta. The TE lineage depends on the transcription factor Cdx2. However, when Cdx2...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319684/ https://www.ncbi.nlm.nih.gov/pubmed/25512302 http://dx.doi.org/10.1016/j.ydbio.2014.12.004 |