Cargando…

Herpes Simplex Virus 2 (HSV-2) Infected Cell Proteins Are among the Most Dominant Antigens of a Live-Attenuated HSV-2 Vaccine

Virion glycoproteins such as glycoprotein D (gD) are believed to be the dominant antigens of herpes simplex virus 2 (HSV-2). We have observed that mice immunized with a live HSV-2 ICP0 (-) mutant virus, HSV-2 0ΔNLS, are 10 to 100 times better protected against genital herpes than mice immunized with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Geltz, Joshua J., Gershburg, Edward, Halford, William P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319894/ https://www.ncbi.nlm.nih.gov/pubmed/25658852 http://dx.doi.org/10.1371/journal.pone.0116091

Ejemplares similares

Pan-HSV-2 IgG Antibody in Vaccinated Mice and Guinea Pigs Correlates with Protection against Herpes Simplex Virus 2
por: Halford, William P., et al.
Publicado: (2013)

Assessment of Two Novel Live-Attenuated Vaccine Candidates for Herpes Simplex Virus 2 (HSV-2) in Guinea Pigs
por: Joyce, Jonathan D., et al.
Publicado: (2021)

A Live-Attenuated HSV-2 ICP0 (−) Virus Elicits 10 to 100 Times Greater Protection against Genital Herpes than a Glycoprotein D Subunit Vaccine
por: Halford, William P., et al.
Publicado: (2011)

The UL13 and US3 Protein Kinases of Herpes Simplex Virus 1 Cooperate to Promote the Assembly and Release of Mature, Infectious Virions
por: Gershburg, Svetlana, et al.
Publicado: (2015)

A Replication-Defective Herpes Simplex Virus (HSV)-2 Vaccine, HSV529, is Safe and Well-Tolerated in Adults with or without HSV Infection and Induces Significant HSV-2-Specific Antibody Responses in HSV Seronegative Individuals
por: Dropulic, Lesia, et al.
Publicado: (2017)

A Herpes Simplex Virus 2 (HSV-2) Glycoprotein D-expressing Nonreplicating Dominant-Negative HSV-2 Virus Vaccine Is Superior to a gD2 Subunit Vaccine against HSV-2 Genital Infection in Guinea Pigs
por: Zhang, Pengwei, et al.
Publicado: (2014)

Immunization with a dominant-negative recombinant Herpes Simplex Virus (HSV) type 1 protects against HSV-2 genital disease in guinea pigs
por: Brans, Richard, et al.
Publicado: (2010)

Rational Design of Live-Attenuated Vaccines against Herpes Simplex Viruses
por: Stanfield, Brent A., et al.
Publicado: (2021)

Antibodies Are Required for Complete Vaccine-Induced Protection against Herpes Simplex Virus 2
por: Halford, William P., et al.
Publicado: (2015)

Comparative Evaluation of AmpliVue HSV 1+2 Assay with ELVIS Culture for Detecting Herpes Simplex Virus 1 (HSV-1) and HSV-2 in Clinical Specimens
por: Granato, Paul A., et al.
Publicado: (2015)

Herpes simplex virus 2 (HSV-2) evolves faster in cell culture than HSV-1 by generating greater genetic diversity
por: López-Muñoz, Alberto Domingo, et al.
Publicado: (2021)

Herpes Simplex Virus Mistyping due to HSV-1 × HSV-2 Interspecies Recombination in Viral Gene Encoding Glycoprotein B
por: Casto, Amanda M., et al.
Publicado: (2020)

Effect of Copper Acyclovir Complexes on Herpes Simplex Virus Type 1 and Type 2 (HSV-1, HSV-2) Infection in Cultured Cells
por: Panteva, M., et al.
Publicado: (1998)

Pneumomediastinum and Pneumothorax Associated with Herpes Simplex Virus (HSV) Pneumonia
por: López-Rivera, Fermín, et al.
Publicado: (2018)

Correction: Effect of Copper Acyclovir Complexes on Herpes Simplex Virus Type 1 and Type 2 (HSV-1, HSV-2) Infection in Cultured Cells
por: Panteva, M., et al.
Publicado: (1998)

A System for Creating Stable Cell Lines that Express a Gene of Interest from a Bidirectional and Regulatable Herpes Simplex Virus Type 1 Promoter
por: Chambers, Christopher B., et al.
Publicado: (2015)

The population impact of herpes simplex virus type 2 (HSV-2) vaccination on the incidence of HSV-2, HIV and genital ulcer disease in South Africa: a mathematical modelling study
por: Stone, Jack, et al.
Publicado: (2023)

An Adenovirus-Based Recombinant Herpes Simplex Virus 2 (HSV-2) Therapeutic Vaccine Is Highly Protective against Acute and Recurrent HSV-2 Disease in a Guinea Pig Model
por: Wan, Mingming, et al.
Publicado: (2023)

1410. Neonatal Herpes Simplex Virus (HSV) Infection: Is It the Only Pathogen?
por: Dendi, Alvaro, et al.
Publicado: (2020)

Disseminated Herpes Simplex Virus-2 (HSV-2) as a Cause of Viral Hepatitis in an Immunocompetent Host
por: Srinivasan, Dushyanth, et al.
Publicado: (2021)

Persistence of mucosal T cell responses to herpes simplex virus type 2 (HSV-2) in the female genital tract
por: Posavad, Christine M., et al.
Publicado: (2014)

No Role of Herpes Simplex Virus Type 2 (HSV-2) Infection on HIV Progression in Naïve HIV Patients
por: Mohraz, Minoo, et al.
Publicado: (2018)

False Positive PCR for Herpes Simplex Virus (HSV) in Childhood CNS Infections
por: Sasan, M S
Publicado: (2012)

Intramuscular vaccination of mice with the human herpes simplex virus type-1(HSV-1) VC2 vaccine, but not its parental strain HSV-1(F) confers full protection against lethal ocular HSV-1 (McKrae) pathogenesis
por: Naidu, Shan K., et al.
Publicado: (2020)

Enhancement of Herpes Simplex Virus (HSV) Infection by Seminal Plasma and Semen Amyloids Implicates a New Target for the Prevention of HSV Infection
por: Torres, Lilith, et al.
Publicado: (2015)

Herpes Simplex Virus Type 2 Seroprevalence in Korea: Rapid Increase of HSV-2 Seroprevalence in the 30s in the Southern Part
por: Shin, Haeng Seop, et al.
Publicado: (2007)

Effectiveness of Early Antiviral Therapy in Disseminated Neonatal Herpes Simplex Virus 2 (HSV-2) with Fulminant Hepatic Failure
por: Mirchandani, Divya, et al.
Publicado: (2017)

Enrichment of herpes simplex virus type 2 (HSV-2) reactive mucosal T cells in the human female genital tract
por: Posavad, Christine M., et al.
Publicado: (2017)

An Attenuated Herpes Simplex Virus Type 1 (HSV1) Encoding the HIV-1 Tat Protein Protects Mice from a Deadly Mucosal HSV1 Challenge
por: Sicurella, Mariaconcetta, et al.
Publicado: (2014)

THE EFFECT OF GESTATIONAL AGE AND LABOR UPON INTRACELLULAR SURVIVAL OF HERPES SIMPLEX VIRUS (HSV)
por: Andersen, Richard D, et al.
Publicado: (1984)

Herpes simplex (HSV) viral load in bronchoalveolar lavage: risk factors and clinical outcome
por: Linssen, C.F.M., et al.
Publicado: (2006)

Use of "biokit HSV-2 Rapid Assay" to improve the positive predictive value of Focus HerpeSelect HSV-2 ELISA
por: Morrow, Rhoda Ashley, et al.
Publicado: (2005)

Antibody to HSV gD peptide induced by vaccination does not protect against HSV-2 infection in HSV-2 seronegative women
por: Gilbert, Peter B., et al.
Publicado: (2017)

Circulating herpes simplex type 1 (HSV-1)-specific CD8(+ )T cells do not access HSV-1 latently infected trigeminal ganglia
por: Himmelein, Susanne, et al.
Publicado: (2011)

Earlier menarche is associated with a higher prevalence of Herpes simplex type-2 (HSV-2) in young women in rural Malawi
por: Glynn, Judith R, et al.
Publicado: (2014)

Virus-Specific Immune Memory at Peripheral Sites of Herpes Simplex Virus Type 2 (HSV-2) Infection in Guinea Pigs
por: Xia, Jingya, et al.
Publicado: (2014)

Correction: Use of "biokitHSV-2 Rapid Assay" to improve the positive predictive value of Focus HerpeSelect HSV-2 ELISA
por: Morrow, Rhoda Ashley, et al.
Publicado: (2007)

Effect of Complexes of Cobalt With Aminoacids on the Replication of Herpes Simplex Virus Type 1 (HSV-1)
por: Varadinova, T., et al.
Publicado: (1996)

Herpes Simplex Virus (HSV-1) Encephalitis Mimicking Glioblastoma: Case Report and Review of the Literature
por: Cunha, Burke A., et al.
Publicado: (2014)

Herpes Simplex Virus-Type1 (HSV-1) Impairs DNA Repair in Cortical Neurons
por: De Chiara, Giovanna, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_2lccc7q5lrr0aitlh3jrgthdp3