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Insights into the Cellular Function of YhdE, a Nucleotide Pyrophosphatase from Escherichia coli

YhdE, a Maf-like protein in Escherichia coli, exhibits nucleotide pyrophosphatase (PPase) activity, yet its cellular function remains unknown. Here, we characterized the PPase activity of YhdE on dTTP, UTP and TTP and determined two crystal structures of YhdE, revealing ‘closed’ and ‘open’ conformat...

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Detalles Bibliográficos
Autores principales:	Jin, Jin, Wu, Ruijuan, Zhu, Jia, Yang, Shaoyuan, Lei, Zhen, Wang, Nan, Singh, Vinay K., Zheng, Jimin, Jia, Zongchao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319933/ https://www.ncbi.nlm.nih.gov/pubmed/25658941 http://dx.doi.org/10.1371/journal.pone.0117823

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