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Multimodal MRI-Based Study in Patients with SPG4 Mutations

Mutations in the SPG4 gene (SPG4-HSP) are the most frequent cause of hereditary spastic paraplegia, but the extent of the neurodegeneration related to the disease is not yet known. Therefore, our objective is to identify regions of the central nervous system damaged in patients with SPG4-HSP using a...

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Detalles Bibliográficos
Autores principales:	Rezende, Thiago J. R., de Albuquerque, Milena, Lamas, Gustavo M., Martinez, Alberto R. M., Campos, Brunno M., Casseb, Raphael F., Silva, Cynthia B., Branco, Lucas M. T., D'Abreu, Anelyssa, Lopes-Cendes, Iscia, Cendes, Fernando, França, Marcondes C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320056/ https://www.ncbi.nlm.nih.gov/pubmed/25658484 http://dx.doi.org/10.1371/journal.pone.0117666

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