Cargando…

Isolation and Functional Characterization of the Novel Clostridium botulinum Neurotoxin A8 Subtype

Botulism is a severe neurological disease caused by the complex family of botulinum neurotoxins (BoNT). Based on the different serotypes known today, a classification of serotype variants termed subtypes has been proposed according to sequence diversity and immunological properties. However, the rel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kull, Skadi, Schulz, K. Melanie, Strotmeier, Jasmin Weisemann née, Kirchner, Sebastian, Schreiber, Tanja, Bollenbach, Alexander, Dabrowski, P. Wojtek, Nitsche, Andreas, Kalb, Suzanne R., Dorner, Martin B., Barr, John R., Rummel, Andreas, Dorner, Brigitte G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320087/ https://www.ncbi.nlm.nih.gov/pubmed/25658638 http://dx.doi.org/10.1371/journal.pone.0116381

Ejemplares similares

Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin
por: Weisemann, Jasmin, et al.
Publicado: (2016)

Optimization of SNAP-25 and VAMP-2 Cleavage by Botulinum Neurotoxin Serotypes A–F Employing Taguchi Design-of-Experiments
por: von Berg, Laura, et al.
Publicado: (2019)

De novo subtype and strain identification of botulinum neurotoxin type B through toxin proteomics
por: Kalb, Suzanne R., et al.
Publicado: (2012)

Botulinum Neurotoxin F Subtypes Cleaving the VAMP-2 Q(58)–K(59) Peptide Bond Exhibit Unique Catalytic Properties and Substrate Specificities
por: Sikorra, Stefan, et al.
Publicado: (2018)

A lipid-binding loop of botulinum neurotoxin serotypes B, DC and G is an essential feature to confer their exquisite potency
por: Stern, Daniel, et al.
Publicado: (2018)

Functional detection of botulinum neurotoxin serotypes A to F by monoclonal neoepitope-specific antibodies and suspension array technology
por: von Berg, Laura, et al.
Publicado: (2019)

Construction and validation of safe Clostridium botulinum Group II surrogate strain producing inactive botulinum neurotoxin type E toxoid
por: Nowakowska, Maria B., et al.
Publicado: (2022)

Generation and Characterization of Six Recombinant Botulinum Neurotoxins as Reference Material to Serve in an International Proficiency Test
por: Weisemann, Jasmin, et al.
Publicado: (2015)

Crystal Structure of the Receptor-Binding Domain of Botulinum Neurotoxin Type HA, Also Known as Type FA or H
por: Yao, Guorui, et al.
Publicado: (2017)

Qualitative and Quantitative Detection of Botulinum Neurotoxins from Complex Matrices: Results of the First International Proficiency Test
por: Worbs, Sylvia, et al.
Publicado: (2015)

Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity
por: Lee, Kwangkook, et al.
Publicado: (2013)

The 25 kDa H(CN) Domain of Clostridial Neurotoxins Is Indispensable for Their Neurotoxicity
por: Deppe, Julian, et al.
Publicado: (2020)

A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1
por: Lam, Kwok-ho, et al.
Publicado: (2018)

A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding
por: Yao, Guorui, et al.
Publicado: (2017)

Innovative and Highly Sensitive Detection of Clostridium perfringens Enterotoxin Based on Receptor Interaction and Monoclonal Antibodies
por: Neumann, Thea, et al.
Publicado: (2021)

Historical Perspectives and Guidelines for Botulinum Neurotoxin Subtype Nomenclature
por: Peck, Michael W., et al.
Publicado: (2017)

Purification and Characterization of Botulinum Neurotoxin FA from a Genetically Modified Clostridium botulinum Strain
por: Pellett, Sabine, et al.
Publicado: (2016)

Conjugative Botulinum Neurotoxin-Encoding Plasmids in Clostridium botulinum
por: Marshall, Kristin M., et al.
Publicado: (2010)

Reoccurrence of botulinum neurotoxin subtype A3 inducing food-borne botulism, Slovakia, 2015
por: Mad’arová, Lucia, et al.
Publicado: (2017)

Analysis of a unique Clostridium botulinum strain from the Southern hemisphere producing a novel type E botulinum neurotoxin subtype
por: Raphael, Brian H, et al.
Publicado: (2012)

Draft Genome Sequence of Bivalent Clostridium botulinum Strain IBCA10-7060, Encoding Botulinum Neurotoxin B and a New FA Mosaic Type
por: Gonzalez-Escalona, Narjol, et al.
Publicado: (2014)

Regulatory Networks Controlling Neurotoxin Synthesis in Clostridium botulinum and Clostridium tetani
por: Popoff, Michel R., et al.
Publicado: (2022)

Recommended Mass Spectrometry-Based Strategies to Identify Botulinum Neurotoxin-Containing Samples
por: Kalb, Suzanne R., et al.
Publicado: (2015)

Detection of the HA-33 protein in botulinum neurotoxin type G complex by mass spectrometry
por: Kalb, Suzanne R., et al.
Publicado: (2015)

Botulinum Neurotoxins: Qualitative and Quantitative Analysis Using the Mouse Phrenic Nerve Hemidiaphragm Assay (MPN)
por: Bigalke, Hans, et al.
Publicado: (2015)

Botulinum Neurotoxin Detection and Differentiation by Mass Spectrometry
por: Barr, John R., et al.
Publicado: (2005)

Posttranslational Regulation of Botulinum Neurotoxin Production in Clostridium botulinum Hall A-hyper
por: Inzalaco, Heather N’te, et al.
Publicado: (2021)

Recommended Immunological Strategies to Screen for Botulinum Neurotoxin-Containing Samples
por: Simon, Stéphanie, et al.
Publicado: (2015)

Preface Biological Toxins—Ancient Molecules Posing a Current Threat
por: Dorner, Brigitte G., et al.
Publicado: (2015)

Genome sequence of Clostridium sporogenes DSM 795(T), an amino acid-degrading, nontoxic surrogate of neurotoxin-producing Clostridium botulinum
por: Poehlein, Anja, et al.
Publicado: (2015)

Sensitive detection of type G botulinum neurotoxin through Endopep-MS peptide substrate optimization
por: Wang, Dongxia, et al.
Publicado: (2019)

Genomic and Phenotypic Characterization of Clostridium botulinum Isolates from an Infant Botulism Case Suggests Adaptation Signatures to the Gut
por: Douillard, François P., et al.
Publicado: (2022)

Binding of Clostridium botulinum neurotoxin to the presynaptic membrane in the central nervous system
Publicado: (1979)

Independent evolution of neurotoxin and flagellar genetic loci in proteolytic Clostridium botulinum
por: Carter, Andrew T, et al.
Publicado: (2009)

Genomes, neurotoxins and biology of Clostridium botulinum Group I and Group II
por: Carter, Andrew T., et al.
Publicado: (2015)

Insights into the evolutionary origins of clostridial neurotoxins from analysis of the Clostridium botulinum strain A neurotoxin gene cluster
por: Doxey, Andrew C, et al.
Publicado: (2008)

Endogenous CRISPR-Cas Systems in Group I Clostridium botulinum and Clostridium sporogenes Do Not Directly Target the Botulinum Neurotoxin Gene Cluster
por: Wentz, Travis G., et al.
Publicado: (2022)

Selection and Development of Nontoxic Nonproteolytic Clostridium botulinum Surrogate Strains for Food Challenge Testing
por: Poortmans, Marijke, et al.
Publicado: (2022)

On Botulinum Neurotoxin Variability
por: Montecucco, Cesare, et al.
Publicado: (2015)

Two-Component Systems Are Involved in the Regulation of Botulinum Neurotoxin Synthesis in Clostridium botulinum Type A Strain Hall
por: Connan, Chloé, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_qrfcfb8105jitvk8t4re32g941