Binding of Kif23-iso1/CHO1 to 14-3-3 Is Regulated by Sequential Phosphorylations at Two LATS Kinase Consensus Sites

Kif23 kinesin is an essential actor of cytokinesis in animals. It exists as two major isoforms, known as MKLP1 and CHO1, the longest of which, CHO1, contains two HXRXXS/T NDR/LATS kinase consensus sites. We demonstrate that these two sites are readily phosphorylated by NDR and LATS kinases in vitro,...

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Detalles Bibliográficos
Autores principales: Fesquet, Didier, De Bettignies, Geoffroy, Bellis, Michel, Espeut, Julien, Devault, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320110/
https://www.ncbi.nlm.nih.gov/pubmed/25658096
http://dx.doi.org/10.1371/journal.pone.0117857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320110/
https://www.ncbi.nlm.nih.gov/pubmed/25658096
http://dx.doi.org/10.1371/journal.pone.0117857

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