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NK cell immunesenescence is increased by psychological but not physical stress in older adults associated with raised cortisol and reduced perforin expression

NK cell cytotoxicity (NKCC) reduces with age and this has been associated previously with increased mortality. The immune response is also modulated by stress, and here, we assessed the effect of the physical stress of hip fracture and the psychological stress of depression on NKCC in an aged immune...

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Detalles Bibliográficos
Autores principales: Duggal, Niharika Arora, Upton, Jane, Phillips, Anna C., Hampson, Peter, Lord, Janet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320126/
https://www.ncbi.nlm.nih.gov/pubmed/25663421
http://dx.doi.org/10.1007/s11357-015-9748-2