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The CHEK2 1100delC allelic variant is not present in familial and sporadic breast cancer cases from Moroccan population
PURPOSE: The cell-cycle checkpoint kinase 2 (CHEK2) is an important signal transducer of cellular responses to DNA damage, whose defects has been associated with increased risk for breast cancer. The CHEK2 1100delC mutation has been reported to confer a twofold increased risk of breast cancer among...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320163/ https://www.ncbi.nlm.nih.gov/pubmed/25674498 http://dx.doi.org/10.1186/s40064-014-0778-5 |