Channel-mediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic NMDA receptors

BACKGROUND: Activation of G protein coupled receptor (GPCR) in astrocytes leads to Ca(2+)-dependent glutamate release via Bestrophin 1 (Best1) channel. Whether receptor-mediated glutamate release from astrocytes can regulate synaptic plasticity remains to be fully understood. RESULTS: We show here t...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Hyungju, Han, Kyung-Seok, Seo, Jinsoo, Lee, Jaekwang, Dravid, Shashank M, Woo, Junsung, Chun, Heejung, Cho, Sukhee, Bae, Jin Young, An, Heeyoung, Koh, Woohyun, Yoon, Bo-Eun, Berlinguer-Palmini, Rolando, Mannaioni, Guido, Traynelis, Stephen F, Bae, Yong Chul, Choi, Se-Young, Lee, C Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320468/
https://www.ncbi.nlm.nih.gov/pubmed/25645137
http://dx.doi.org/10.1186/s13041-015-0097-y

Ejemplares similares

Ejemplares similares