Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) promotes glioma cell invasion through induction of NF-κB-inducing kinase (NIK) and noncanonical NF-κB signaling

BACKGROUND: High-grade gliomas are one of the most invasive and therapy-resistant cancers. We have recently shown that noncanonical NF-κB/RelB signaling is a potent driver of tumorigenesis and invasion in the aggressive, mesenchymal subtype of glioma. However, the relevant signals that induce activa...

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Detalles Bibliográficos
Autores principales: Cherry, Evan M, Lee, Dong W, Jung, Ji-Ung, Sitcheran, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320546/
https://www.ncbi.nlm.nih.gov/pubmed/25622756
http://dx.doi.org/10.1186/s12943-014-0273-1

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