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Intratumoral heterogeneity in a minority of ovarian low-grade serous carcinomas
BACKGROUND: Ovarian low-grade serous carcinoma (LGSC) has fewer mutations than ovarian high-grade serous carcinoma (HGSC) and a less aggressive clinical course. However, an overwhelming majority of LGSC patients do not respond to conventional chemotherapy resulting in a poor long-term prognosis comp...
Autores principales: | Tone, Alicia A, McConechy, Melissa K, Yang, Winnie, Ding, Jiarui, Yip, Stephen, Kong, Esther, Wong, Kwong-Kwok, Gershenson, David M, Mackay, Helen, Shah, Sohrab, Gilks, Blake, Tinker, Anna V, Clarke, Blaise, McAlpine, Jessica N, Huntsman, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320586/ https://www.ncbi.nlm.nih.gov/pubmed/25523272 http://dx.doi.org/10.1186/1471-2407-14-982 |
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