Increased in vivo mitochondrial oxygenation with right ventricular failure induced by pulmonary arterial hypertension: mitochondrial inhibition as driver of cardiac failure?

BACKGROUND: The leading cause of mortality due to pulmonary arterial hypertension (PAH) is failure of the cardiac right ventricle. It has long been hypothesized that during the development of chronic cardiac failure the heart becomes energy deprived, possibly due to shortage of oxygen at the level o...

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Detalles Bibliográficos
Autores principales: Balestra, Gianmarco M, Mik, Egbert G, Eerbeek, Otto, Specht, Patricia AC, van der Laarse, Willem J, Zuurbier, Coert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320611/
https://www.ncbi.nlm.nih.gov/pubmed/25645252
http://dx.doi.org/10.1186/s12931-015-0178-6

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