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Fluorine-Decoupled Carbon Spectroscopy for the Determination of Configuration at Fully Substituted, Trifluoromethyl- and Perfluoroalkyl-Bearing Carbons: Comparison with (19)F–(1)H Heteronuclear Overhauser Effect Spectroscopy

[Image: see text] The synthesis of a series of α-trifluoromethylcyclohexanols and analogous trimethylsilyl ethers by addition of the Ruppert–Prakash reagent to substituted cyclohexanones is presented. A method for the assignment of configuration of such compounds, of related α-trifluoromethylcyclohe...

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Detalles Bibliográficos
Autores principales: Mandhapati, Appi Reddy, Kato, Takayuki, Matsushita, Takahiko, Ksebati, Bashar, Vasella, Andrea, Böttger, Erik C., Crich, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320651/
https://www.ncbi.nlm.nih.gov/pubmed/25561269
http://dx.doi.org/10.1021/jo502677a