The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection

Immune responses are tightly regulated to ensure efficient pathogen clearance while avoiding tissue damage. Here we report that SET domain bifurcated 2 (Setdb2) was the only protein lysine methyltransferase induced during influenza virus infection. Setdb2 expression depended on type-I interferon sig...

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Detalles Bibliográficos
Autores principales: Schliehe, Christopher, Flynn, Elizabeth K., Vilagos, Bojan, Richson, Udochuku, Swaminanthan, Savitha, Bosnjak, Berislav, Bauer, Lisa, Kandasamy, Richard K., Griesshammer, Isabel M., Kosack, Lindsay, Schmitz, Frank, Litvak, Vladimir, Sissons, James, Lercher, Alexander, Bhattacharya, Anannya, Khamina, Kseniya, Trivett, Anna L., Tessarollo, Lino, Mesteri, Ildiko, Hladik, Anastasiya, Merkler, Doron, Kubicek, Stefan, Knapp, Sylvia, Epstein, Michelle M., Symer, David E., Aderem, Alan, Bergthaler, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320687/
https://www.ncbi.nlm.nih.gov/pubmed/25419628
http://dx.doi.org/10.1038/ni.3046

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