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Periodontal Disease and Late-Onset Aortic Prosthetic Vascular Graft Infection

Prosthetic vascular graft infection (PVGI) is a rare but significant complication of arterial reconstructive surgery. Although the relative risk is low, the clinical consequences can be catastrophic. Microbiological data on causative bacteria are limited. We present four cases of late-onset PVGI. Us...

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Detalles Bibliográficos
Autores principales: Thomas, Stephanie, Ghosh, Jonathan, Porter, Johnathan, Cockcroft, Adele, Rautemaa-Richardson, Riina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320805/
https://www.ncbi.nlm.nih.gov/pubmed/25685592
http://dx.doi.org/10.1155/2015/768935
Descripción
Sumario:Prosthetic vascular graft infection (PVGI) is a rare but significant complication of arterial reconstructive surgery. Although the relative risk is low, the clinical consequences can be catastrophic. Microbiological data on causative bacteria are limited. We present four cases of late-onset PVGI. Using a culture-independent nucleic acid amplification method for analysis of intraoperative samples, the presence of bacteria highly suggestive of an oral source was reported. Examination by an oral health specialist confirmed the presence of chronic periodontal disease. We hypothesize that chronic oral infection may be a previously unreported risk factor for the development of late-onset PVGI.