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Oncogenic KRAS promotes malignant brain tumors in zebrafish
BACKGROUND: Zebrafish have been used as a vertebrate model to study human cancers such as melanoma, rhabdomyosarcoma, liver cancer, and leukemia as well as for high-throughput screening of small molecules of therapeutic value. However, they are just emerging as a model for human brain tumors, which...
Autores principales: | Ju, Bensheng, Chen, Wenbiao, Orr, Brent A, Spitsbergen, Jan M, Jia, Sujuan, Eden, Christopher J, Henson, Hannah E, Taylor, Michael R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320811/ https://www.ncbi.nlm.nih.gov/pubmed/25644510 http://dx.doi.org/10.1186/s12943-015-0288-2 |
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