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Prognostic relevance of acquired uniparental disomy in serous ovarian cancer

BACKGROUND: Acquired uniparental disomy (aUPD) can lead to homozygosity for tumor suppressor genes or oncogenes. Our purpose is to determine the frequency and profile aUPD regions in serous ovarian cancer (SOC) and investigated the association of aUPD with clinical features and patient outcomes. MET...

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Detalles Bibliográficos
Autores principales:	Tuna, Musaffe, Ju, Zhenlin, Smid, Marcel, Amos, Christopher I, Mills, Gordon B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320828/ https://www.ncbi.nlm.nih.gov/pubmed/25644622 http://dx.doi.org/10.1186/s12943-015-0289-1

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