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SPOCK1 as a potential cancer prognostic marker promotes the proliferation and metastasis of gallbladder cancer cells by activating the PI3K/AKT pathway

BACKGROUND: Gallbladder cancer (GBC) is a leading cause of cancer-related death worldwide, and its prognosis remains poor, with 5-year survival of approximately 5%. In this study, we analyzed the involvement of a novel proteoglycan, Sparc/osteonectin, cwcv, and kazal-like domains proteoglycan 1 (SPO...

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Detalles Bibliográficos
Autores principales: Shu, Yi-Jun, Weng, Hao, Ye, Yuan-Yuan, Hu, Yun-Ping, Bao, Run-Fa, Cao, Yang, Wang, Xu-An, Zhang, Fei, Xiang, Shan-Shan, Li, Huai-Feng, Wu, Xiang-Song, Li, Mao-Lan, Jiang, Lin, Lu, Wei, Han, Bao-San, Jie, Zhi-Gang, Liu, Ying-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320842/
https://www.ncbi.nlm.nih.gov/pubmed/25623055
http://dx.doi.org/10.1186/s12943-014-0276-y