Icariin Intervenes in Cardiac Inflammaging through Upregulation of SIRT6 Enzyme Activity and Inhibition of the NF-Kappa B Pathway

The aim of the study was to investigate the effect of icariin (ICA) on cardiac aging through its effects on the SIRT6 enzyme and on the NF-κB pathway. Investigating the effect of ICA on the enzymatic activity of histone deacetylase SIRT6 revealed a concentration of 10(−8) mol/L ICA had a maximum act...

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Detalles Bibliográficos
Autores principales: Chen, Yang, Sun, Tao, Wu, Junzhen, Kalionis, Bill, Zhang, Changcheng, Yuan, Ding, Huang, Jianhua, Cai, Waijiao, Fang, Hong, Xia, Shijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320867/
https://www.ncbi.nlm.nih.gov/pubmed/25688369
http://dx.doi.org/10.1155/2015/895976

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