Zeaxanthin Inhibits Hypoxia-Induced VEGF Secretion by RPE Cells through Decreased Protein Levels of Hypoxia-Inducible Factors-1α

Hypoxia is the most important stimulus leading to upregulation of VEGF in the retina and this is caused by accumulation of hypoxia-inducible factors-1α (HIF-1α) protein. The effects of zeaxanthin, a natural phytochemical, on the VEGF and HIF-1α expression in the primary culture of human retinal pigm...

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Detalles Bibliográficos
Autores principales: Rosen, Richard, Vagaggini, Tommaso, Chen, Yueqin, Hu, Dan-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320873/
https://www.ncbi.nlm.nih.gov/pubmed/25688362
http://dx.doi.org/10.1155/2015/687386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320873/
https://www.ncbi.nlm.nih.gov/pubmed/25688362
http://dx.doi.org/10.1155/2015/687386

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