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Overdominance Effect of the Bovine Ghrelin Receptor (GHSR1a)-DelR242 Locus on Growth in Japanese Shorthorn Weaner Bulls: Heterozygote Advantage in Bull Selection and Molecular Mechanisms

Ghrelin and the ghrelin receptor (GHSR1a) are involved in growth hormone secretion, food intake, and several other important functions. Ghrelin acts on GHSR1a and induces signal transduction via the Gαq subunit. In our previous study, we identified the DelR242 (3R) allele, a truncated 3-arginine res...

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Detalles Bibliográficos
Autores principales: Komatsu, Masanori, Sato, Yoichi, Negami, Tatsuki, Terada, Tohru, Sasaki, Osamu, Yasuda, Jumpei, Arakawa, Aisaku, Yoshida, Chikara, Takahashi, Hideaki, Malau-Aduli, Aduli E. O., Suzuki, Keiichi, Shimizu, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321035/
https://www.ncbi.nlm.nih.gov/pubmed/25538099
http://dx.doi.org/10.1534/g3.114.016105