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Nanocomplexation of thrombin with cationic amylose derivative for improved stability and hemostatic efficacy
As a topical hemostatic agent, thrombin has wide application for many surgical treatments. However, native thrombin always suffers from its physical and chemical instabilities. In this work, a nanocomplexation strategy was developed for modifying the stability and hemostatic efficacy of thrombin, in...
Autores principales: | Zhuang, Baoxiong, Li, Zhihua, Pang, Jiadong, Li, Wenbin, Huang, Pinbo, Wang, Jie, Zhou, Yu, Lin, Qing, Zhou, Quanbo, Ye, Xiao, Ye, Huilin, Liu, Yimin, Zhang, Li-Ming, Chen, Rufu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321601/ https://www.ncbi.nlm.nih.gov/pubmed/25673989 http://dx.doi.org/10.2147/IJN.S72553 |
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