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Histone acetyltransferase inhibitor II induces apoptosis in glioma cell lines via the p53 signaling pathway
BACKGROUND: Histone acetyltransferase (HAT) inhibitors can inhibit proliferation and induce apoptosis in cancer cell lines. The novel cell-permeable p300/CREB-binding protein (CBP)-selective HAT inhibitor HATi II can reduce histone H3 acetylation and induce chromatin condensation in HeLa cells. Here...
Autores principales: | Xu, Li-Xiao, Li, Zhi-Heng, Tao, Yan-Fang, Li, Rong-Hu, Fang, Fang, Zhao, He, Li, Gang, Li, Yan-Hong, Wang, Jian, Feng, Xing, Pan, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321714/ https://www.ncbi.nlm.nih.gov/pubmed/25523932 http://dx.doi.org/10.1186/s13046-014-0108-3 |
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