Identification of Immunodominant CD4-Restricted Epitopes Co-Located with Antibody Binding Sites in Individuals Vaccinated with ALVAC-HIV and AIDSVAX B/E

We performed fine epitope mapping of the CD4+ responses in the ALVAC-HIV-AIDSVAX B/E prime-boost regimen in the Thai Phase III trial (RV144). Non-transformed Env-specific T cell lines established from RV144 vaccinees were used to determine the fine epitope mapping of the V2 and C1 responses and the...

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Detalles Bibliográficos
Autores principales: Ratto-Kim, Silvia, de Souza, Mark S., Currier, Jeffrey R., Karasavvas, Nicos, Sidney, John, Rolland, Morgane, Valencia-Micolta, Anais, Madnote, Sirinan, Sette, Alessandro, Nitayaphan, Sorachai, Pitisuttuthum, Punnee, Kaewkungwal, Jaranit, Rerks-Ngarm, Supachai, O’Connell, Robert, Michael, Nelson, Robb, Merlin L., Marovich, Mary, Kim, Jerome H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321833/
https://www.ncbi.nlm.nih.gov/pubmed/25665096
http://dx.doi.org/10.1371/journal.pone.0115582

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