Cargando…
The Effect of Hyperglycaemia on In Vitro Cytokine Production and Macrophage Infection with Mycobacterium tuberculosis
Type 2 diabetes mellitus is an established risk factor for tuberculosis but the underlying mechanisms are largely unknown. We examined the effects of hyperglycaemia, a hallmark of diabetes, on the cytokine response to and macrophage infection with Mycobacterium tuberculosis. Increasing in vitro gluc...
Autores principales: | Lachmandas, Ekta, Vrieling, Frank, Wilson, Louis G., Joosten, Simone A., Netea, Mihai G., Ottenhoff, Tom H., van Crevel, Reinout |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322041/ https://www.ncbi.nlm.nih.gov/pubmed/25664765 http://dx.doi.org/10.1371/journal.pone.0117941 |
Ejemplares similares
-
Tissue Metabolic Changes Drive Cytokine Responses to Mycobacterium tuberculosis
por: Lachmandas, Ekta, et al.
Publicado: (2018) -
Innate Immune Recognition of Mycobacterium tuberculosis
por: Kleinnijenhuis, Johanneke, et al.
Publicado: (2011) -
Oxidized low-density lipoprotein (oxLDL) supports Mycobacterium tuberculosis survival in macrophages by inducing lysosomal dysfunction
por: Vrieling, Frank, et al.
Publicado: (2019) -
Rewiring cellular metabolism via the AKT/mTOR pathway contributes to host defence against Mycobacterium tuberculosis in human and murine cells
por: Lachmandas, Ekta, et al.
Publicado: (2016) -
Diabetes Mellitus and Increased Tuberculosis Susceptibility: The Role of Short-Chain Fatty Acids
por: Lachmandas, Ekta, et al.
Publicado: (2016)