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VEGF-A modulates expression of inhibitory checkpoints on CD8(+) T cells in tumors

Immune escape is a prerequisite for tumor development. To avoid the immune system, tumors develop different mechanisms, including T cell exhaustion, which is characterized by expression of immune inhibitory receptors, such as PD-1, CTLA-4, Tim-3, and a progressive loss of function. The recent develo...

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Detalles Bibliográficos
Autores principales:	Voron, Thibault, Colussi, Orianne, Marcheteau, Elie, Pernot, Simon, Nizard, Mevyn, Pointet, Anne-Laure, Latreche, Sabrina, Bergaya, Sonia, Benhamouda, Nadine, Tanchot, Corinne, Stockmann, Christian, Combe, Pierre, Berger, Anne, Zinzindohoue, Franck, Yagita, Hideo, Tartour, Eric, Taieb, Julien, Terme, Magali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322048/ https://www.ncbi.nlm.nih.gov/pubmed/25601652 http://dx.doi.org/10.1084/jem.20140559

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