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ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2

The co-stimulators ICOS (inducible T cell co-stimulator) and CD28 are both important for T follicular helper (TFH) cells, yet their individual contributions are unclear. Here, we show that each molecule plays an exclusive role at different stages of TFH cell development. While CD28 regulated early e...

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Detalles Bibliográficos
Autores principales:	Weber, Jan P., Fuhrmann, Franziska, Feist, Randi K., Lahmann, Annette, Al Baz, Maysun S., Gentz, Lea-Jean, Vu Van, Dana, Mages, Hans W., Haftmann, Claudia, Riedel, René, Grün, Joachim R., Schuh, Wolfgang, Kroczek, Richard A., Radbruch, Andreas, Mashreghi, Mir-Farzin, Hutloff, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322049/ https://www.ncbi.nlm.nih.gov/pubmed/25646266 http://dx.doi.org/10.1084/jem.20141432

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