Cargando…
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials
BACKGROUND: Statins increase the risk of new-onset type 2 diabetes mellitus. We aimed to assess whether this increase in risk is a consequence of inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), the intended drug target. METHODS: We used single nucleotide polymorphisms in the HMGCR ge...
Ejemplares similares
-
The impact of coronary artery disease risk loci on ischemic heart failure severity and prognosis: association analysis in the COntrolled ROsuvastatin multiNAtional trial in heart failure (CORONA)
por: Haver, Vincent G, et al.
Publicado: (2014) -
Association between infection and fever in terminations of pregnancy using misoprostol: a retrospective cohort study
por: Nijman, Tobias A. J., et al.
Publicado: (2017) -
Influence of Induced Blood Pressure Variability on the Assessment of Cerebral Autoregulation in Patients after Cardiac Arrest
por: van den Brule, J. M. D., et al.
Publicado: (2018) -
Drug-induced caspase 8 upregulation sensitises cisplatin-resistant ovarian carcinoma cells to rhTRAIL-induced apoptosis
por: Duiker, E W, et al.
Publicado: (2011) -
The CHORUS honeycomb tracker and its bitstream electronics
por: Uiterwijk, J W E, et al.
Publicado: (1998)