Cargando…

Levetiracetam Ameliorates L-DOPA-Induced Dyskinesia in Hemiparkinsonian Rats Inducing Critical Molecular Changes in the Striatum

L-DOPA-induced dyskinesias (LID) remain a major problem of long-term therapy of Parkinson's disease. Levetiracetam, a new antiepileptic drug, has been shown to reduce LID, but the mechanisms underlying its effects are unknown. In this study, we assessed the effect of levetiracetam on key mediat...

Descripción completa

Detalles Bibliográficos
Autores principales: Du, Huan, Nie, Shuke, Chen, Guiqin, Ma, Kai, Xu, Yan, Zhang, Zhentao, Papa, Stella M., Cao, Xuebing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322303/
https://www.ncbi.nlm.nih.gov/pubmed/25692070
http://dx.doi.org/10.1155/2015/253878