Levetiracetam Ameliorates L-DOPA-Induced Dyskinesia in Hemiparkinsonian Rats Inducing Critical Molecular Changes in the Striatum

L-DOPA-induced dyskinesias (LID) remain a major problem of long-term therapy of Parkinson's disease. Levetiracetam, a new antiepileptic drug, has been shown to reduce LID, but the mechanisms underlying its effects are unknown. In this study, we assessed the effect of levetiracetam on key mediat...

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Detalles Bibliográficos
Autores principales: Du, Huan, Nie, Shuke, Chen, Guiqin, Ma, Kai, Xu, Yan, Zhang, Zhentao, Papa, Stella M., Cao, Xuebing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322303/
https://www.ncbi.nlm.nih.gov/pubmed/25692070
http://dx.doi.org/10.1155/2015/253878

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