Aurora B-dependent phosphorylation of Ataxin-10 promotes the interaction between Ataxin-10 and Plk1 in cytokinesis

Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant neurologic disorder caused by ATTCT expansion in the ATXN10 gene. Previous investigations have identified that depletion of Ataxin-10, the gene product, leads to cellular apoptosis and cytokinesis failure. Herein we identify the mitotic...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Jie, Tian, Chuan, Ding, Yuehe, Li, Zhe, Geng, Qizhi, Xiahou, Zhikai, Wang, Jue, Hou, Wenya, Liao, Ji, Dong, Meng-Qiu, Xu, Xingzhi, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322367/
https://www.ncbi.nlm.nih.gov/pubmed/25666058
http://dx.doi.org/10.1038/srep08360

Ejemplares similares

Ejemplares similares