Cargando…
Computational identification and binding analysis of orphan human cytochrome P450 4X1 enzyme with substrates
BACKGROUND: Cytochrome P450s (CYPs) are important heme-containing proteins, well known for their monooxygenase reaction. The human cytochrome P450 4X1 (CYP4X1) is categorized as “orphan” CYP because of its unknown function. In recent studies it is found that this enzyme is expressed in neurovascular...
Autor principal: | Kumar, Suresh |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322450/ https://www.ncbi.nlm.nih.gov/pubmed/25595103 http://dx.doi.org/10.1186/s13104-015-0976-4 |
Ejemplares similares
-
Molecular modeling and identification of substrate binding site of orphan human cytochrome P450 4F22
por: Kumar, Suresh
Publicado: (2011) -
Bioactivation of Aromatic Amines by Human CYP2W1, An Orphan Cytochrome P450 Enzyme
por: Eun, Chang-Yong, et al.
Publicado: (2010) -
Substrate binding induces structural changes in cytochrome P450cam
por: Sakurai, Keisuke, et al.
Publicado: (2009) -
Evaluation of Luminogenic Substrates as Probe Substrates for Bacterial Cytochrome P450 Enzymes: Application to Mycobacterium tuberculosis
por: Ortega Ugalde, Sandra, et al.
Publicado: (2019) -
Structural Insights into the Mechanism for Recognizing Substrate of the Cytochrome P450 Enzyme TxtE
por: Yu, Feng, et al.
Publicado: (2013)