Crystal structure and biophysical characterization of the nucleoside diphosphate kinase from Leishmania braziliensis

BACKGROUND: Nucleoside diphosphate kinase (NDK) is a housekeeping enzyme that plays key roles in nucleotide recycling and homeostasis in trypanosomatids. It is also secreted by the intracellular parasite Leishmania to modulate the host response. These functions make NDK an attractive target for drug...

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Detalles Bibliográficos
Autores principales: Vieira, Plínio Salmazo, de Giuseppe, Priscila Oliveira, Murakami, Mario Tyago, de Oliveira, Arthur Henrique Cavalcante
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322457/
https://www.ncbi.nlm.nih.gov/pubmed/25643978
http://dx.doi.org/10.1186/s12900-015-0030-8

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