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A Survey on the Status of Hepatitis E Virus Infection Among Slaughterhouse Workers in South Korea
OBJECTIVES: The seroprevalence of hepatitis E virus (HEV) among high-risk groups overseas is high, but studies in these groups are rare in South Korea. We conducted the present study from April to November 2012 to obtain data on the seroprevalence and associated risk factors for HEV among slaughterh...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Korean Society for Preventive Medicine
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322518/ https://www.ncbi.nlm.nih.gov/pubmed/25652711 http://dx.doi.org/10.3961/jpmph.14.048 |
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author | Kim, Byung-Seok Lim, Hyun-Sul Lee, Kwan Min, Young-Sun Yoon, Young-Sil Jeong, Hye-Sook |
author_facet | Kim, Byung-Seok Lim, Hyun-Sul Lee, Kwan Min, Young-Sun Yoon, Young-Sil Jeong, Hye-Sook |
author_sort | Kim, Byung-Seok |
collection | PubMed |
description | OBJECTIVES: The seroprevalence of hepatitis E virus (HEV) among high-risk groups overseas is high, but studies in these groups are rare in South Korea. We conducted the present study from April to November 2012 to obtain data on the seroprevalence and associated risk factors for HEV among slaughterhouse workers in South Korea. METHODS: Slaughterhouse workers from 80 workplaces nationwide were surveyed in South Korea in 2012. The subjects comprised 1848 cases: 1434 slaughter workers and 414 residual products handlers. By visiting 80 slaughterhouses, which were mixed with 75 of which also performed residual products handling, we conducted a questionnaire survey for risk factors and obtained blood samples in order to determine the seropositivity and seroprevalence of HEV. Anti-HEV IgG and IgM were measured using HEV IgG and IgM enzyme-linked immunospecific assay kits and HEV antigen was measured by reverse transcription polymerase chain reaction (RT-PCR). RESULTS: The seropositivity of anti-HEV IgG was 33.5% (slaughter workers 32.8% and residual products handlers 36.2%), and among the seropositive individuals the seroprevalence of anti-HEV IgM was 0.5% (slaughter workers 0.5%, residual products handlers 0.7%). The response rate of HEV-antigen as measured by RT-PCR was 0.2%. Risk factors significantly related to anti-HEV IgG seropositivity were age, sex , and working duration (slaughter workers only). CONCLUSIONS: There were significant risk factors (sex, age, and working duration) for HEV identified in our study. All three positive cases for HEV-antigen by RT-PCR were related to pig slaughter but without statistical significance. To prevent HEV, an educational program and working guidelines may be needed for high risk groups. |
format | Online Article Text |
id | pubmed-4322518 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Korean Society for Preventive Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-43225182015-02-10 A Survey on the Status of Hepatitis E Virus Infection Among Slaughterhouse Workers in South Korea Kim, Byung-Seok Lim, Hyun-Sul Lee, Kwan Min, Young-Sun Yoon, Young-Sil Jeong, Hye-Sook J Prev Med Public Health Original Article OBJECTIVES: The seroprevalence of hepatitis E virus (HEV) among high-risk groups overseas is high, but studies in these groups are rare in South Korea. We conducted the present study from April to November 2012 to obtain data on the seroprevalence and associated risk factors for HEV among slaughterhouse workers in South Korea. METHODS: Slaughterhouse workers from 80 workplaces nationwide were surveyed in South Korea in 2012. The subjects comprised 1848 cases: 1434 slaughter workers and 414 residual products handlers. By visiting 80 slaughterhouses, which were mixed with 75 of which also performed residual products handling, we conducted a questionnaire survey for risk factors and obtained blood samples in order to determine the seropositivity and seroprevalence of HEV. Anti-HEV IgG and IgM were measured using HEV IgG and IgM enzyme-linked immunospecific assay kits and HEV antigen was measured by reverse transcription polymerase chain reaction (RT-PCR). RESULTS: The seropositivity of anti-HEV IgG was 33.5% (slaughter workers 32.8% and residual products handlers 36.2%), and among the seropositive individuals the seroprevalence of anti-HEV IgM was 0.5% (slaughter workers 0.5%, residual products handlers 0.7%). The response rate of HEV-antigen as measured by RT-PCR was 0.2%. Risk factors significantly related to anti-HEV IgG seropositivity were age, sex , and working duration (slaughter workers only). CONCLUSIONS: There were significant risk factors (sex, age, and working duration) for HEV identified in our study. All three positive cases for HEV-antigen by RT-PCR were related to pig slaughter but without statistical significance. To prevent HEV, an educational program and working guidelines may be needed for high risk groups. Korean Society for Preventive Medicine 2015-01 2015-01-15 /pmc/articles/PMC4322518/ /pubmed/25652711 http://dx.doi.org/10.3961/jpmph.14.048 Text en Copyright © 2015 The Korean Society for Preventive Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kim, Byung-Seok Lim, Hyun-Sul Lee, Kwan Min, Young-Sun Yoon, Young-Sil Jeong, Hye-Sook A Survey on the Status of Hepatitis E Virus Infection Among Slaughterhouse Workers in South Korea |
title | A Survey on the Status of Hepatitis E Virus Infection Among Slaughterhouse Workers in South Korea |
title_full | A Survey on the Status of Hepatitis E Virus Infection Among Slaughterhouse Workers in South Korea |
title_fullStr | A Survey on the Status of Hepatitis E Virus Infection Among Slaughterhouse Workers in South Korea |
title_full_unstemmed | A Survey on the Status of Hepatitis E Virus Infection Among Slaughterhouse Workers in South Korea |
title_short | A Survey on the Status of Hepatitis E Virus Infection Among Slaughterhouse Workers in South Korea |
title_sort | survey on the status of hepatitis e virus infection among slaughterhouse workers in south korea |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322518/ https://www.ncbi.nlm.nih.gov/pubmed/25652711 http://dx.doi.org/10.3961/jpmph.14.048 |
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