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Epigenetic mechanisms of induced pluripotency

Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) requires profound alterations in the epigenetic landscape. During reprogramming, a change in chromatin structure resets the gene expression and stabilises self-renewal. Reprogramming is a highly inefficient process, in part due...

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Detalles Bibliográficos
Autores principales:	Gładych, Marta, Andrzejewska, Anastazja, Oleksiewicz, Urszula, Estécio, Marcos R.H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Termedia Publishing House 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322530/ https://www.ncbi.nlm.nih.gov/pubmed/25691819 http://dx.doi.org/10.5114/wo.2014.47135

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