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A co-culture genome-wide RNAi screen with mammary epithelial cells reveals transmembrane signals required for growth and differentiation

INTRODUCTION: The extracellular signals regulating mammary epithelial cell growth are of relevance to understanding the pathophysiology of mammary epithelia, yet they remain poorly characterized. In this study, we applied an unbiased approach to understanding the functional role of signalling molecu...

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Detalles Bibliográficos
Autores principales: Burleigh, Angela, McKinney, Steven, Brimhall, Jazmine, Yap, Damian, Eirew, Peter, Poon, Steven, Ng, Viola, Wan, Adrian, Prentice, Leah, Annab, Lois, Barrett, J Carl, Caldas, Carlos, Eaves, Connie, Aparicio, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322558/
https://www.ncbi.nlm.nih.gov/pubmed/25572802
http://dx.doi.org/10.1186/s13058-014-0510-y

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