Rapid detection of structural variation in a human genome using nanochannel-based genome mapping technology

BACKGROUND: Structural variants (SVs) are less common than single nucleotide polymorphisms and indels in the population, but collectively account for a significant fraction of genetic polymorphism and diseases. Base pair differences arising from SVs are on a much higher order (>100 fold) than poi...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Hongzhi, Hastie, Alex R, Cao, Dandan, Lam, Ernest T, Sun, Yuhui, Huang, Haodong, Liu, Xiao, Lin, Liya, Andrews, Warren, Chan, Saki, Huang, Shujia, Tong, Xin, Requa, Michael, Anantharaman, Thomas, Krogh, Anders, Yang, Huanming, Cao, Han, Xu, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322599/
https://www.ncbi.nlm.nih.gov/pubmed/25671094
http://dx.doi.org/10.1186/2047-217X-3-34

Ejemplares similares

Ejemplares similares