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Design and in vivo evaluation of oxycodone once-a-day controlled-release tablets
The aim of present study was to design oxycodone once-a-day controlled-release (CR) tablets and to perform in vitro/in vivo characterizations. Release profiles to achieve desired plasma concentration versus time curves were established by using simulation software and reported pharmacokinetic parame...
Autores principales: | Kim, Ju-Young, Lee, Sung-Hoon, Park, Chun-Woong, Rhee, Yun-Seok, Kim, Dong-Wook, Park, Junsang, Lee, Moonseok, Seo, Jeong-Woong, Park, Eun-Seok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322610/ https://www.ncbi.nlm.nih.gov/pubmed/25678774 http://dx.doi.org/10.2147/DDDT.S77356 |
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