Cargando…
A marine analgesic peptide, Contulakin-G, and neurotensin are distinct agonists for neurotensin receptors: uncovering structural determinants of desensitization properties
Neurotensin receptors have been studied as molecular targets for the treatment of pain, schizophrenia, addiction, or cancer. Neurotensin (NT) and Contulakin-G, a glycopeptide isolated from a predatory cone snail Conus geographus, share a sequence similarity at the C-terminus, which is critical for a...
Autores principales: | Lee, Hee-Kyoung, Zhang, Liuyin, Smith, Misty D., Walewska, Aleksandra, Vellore, Nadeem A., Baron, Riccardo, McIntosh, J. Michael, White, H. Steve, Olivera, Baldomero M., Bulaj, Grzegorz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322620/ https://www.ncbi.nlm.nih.gov/pubmed/25713532 http://dx.doi.org/10.3389/fphar.2015.00011 |
Ejemplares similares
-
Structure of the agonist-bound neurotensin receptor
por: White, Jim F., et al.
Publicado: (2012) -
Diverse Roles of Neurotensin Agonists in the Central Nervous System
por: Boules, Mona, et al.
Publicado: (2013) -
Neurotensin Agonist Attenuates Nicotine Potentiation to Cocaine Sensitization
por: Fredrickson, Paul, et al.
Publicado: (2014) -
Imaging Neurotensin Receptor in Prostate Cancer With (64)Cu-Labeled Neurotensin Analogs
por: Deng, Huaifu, et al.
Publicado: (2017) -
The Anti-Apoptotic Role of Neurotensin
por: Devader, Christelle, et al.
Publicado: (2013)