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LPS stimulation of purified human platelets is partly dependent on plasma soluble CD14 to secrete their main secreted product, soluble-CD40-Ligand
BACKGROUND: Platelets are instrumental to primary haemostasis; in addition, as they are central to endothelium vascular repair, they play a role in physiological inflammation. Platelets have also been demonstrated to be key players in innate immunity and inflammation, expressing Toll-like receptors...
Autores principales: | Damien, Pauline, Cognasse, Fabrice, Eyraud, Marie-Ange, Arthaud, Charles-Antoine, Pozzetto, Bruno, Garraud, Olivier, Hamzeh-Cognasse, Hind |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322959/ https://www.ncbi.nlm.nih.gov/pubmed/25636826 http://dx.doi.org/10.1186/s12865-015-0067-2 |
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