EBV-driven LMP1 and IFN-γ up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy

PD-L1 expression is a feature of Epstein-Barr virus (EBV) associated malignancies such as nasopharyngeal carcinoma (NPC). Here, we found that EBV-induced latent membrane protein 1 (LMP1) and IFN-γ pathways cooperate to regulate programmed cell death protein 1 ligand (PD-L1). Expression of PD-L1 was...

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Detalles Bibliográficos
Autores principales: Fang, Wenfeng, Zhang, Jianwei, Hong, Shaodong, Zhan, Jianhua, Chen, Nan, Qin, Tao, Tang, Yanna, Zhang, Yaxiong, Kang, Shiyang, Zhou, Ting, Wu, Xuan, Liang, Wenhua, Hu, Zhihuang, Ma, Yuxiang, Zhao, Yuanyuan, Tian, Ying, Yang, Yunpeng, Xue, Cong, Yan, Yue, Hou, Xue, Huang, Peiyu, Huang, Yan, Zhao, Hongyun, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322961/
https://www.ncbi.nlm.nih.gov/pubmed/25361008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322961/
https://www.ncbi.nlm.nih.gov/pubmed/25361008

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