Transcriptomic profiling of taxol-resistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response

Taxol is a mitotoxin widely used to treat human cancers, including of the breast and ovary. However, taxol resistance (txr) limits treatment efficacy in human patients. To study chemoresistance in ovarian cancer, we established txr ovarian carcinoma cells derived from the SKOV3 cell lineage. The cel...

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Detalles Bibliográficos
Autores principales: Sun, Nian-Kang, Huang, Shang-Lang, Chang, Pu-Yuan, Lu, Hsing-Pang, Chao, Chuck C.-K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322968/
https://www.ncbi.nlm.nih.gov/pubmed/25460502

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