The orthologous Tbx transcription factors Omb and TBX2 induce epithelial cell migration and extrusion in vivo without involvement of matrix metalloproteinases

The transcription factors TBX2 and TBX3 are overexpressed in various human cancers. Here, we investigated the effect of overexpressing the orthologous Tbx genes Drosophila optomotor-blind (omb) and human TBX2 in the epithelium of the Drosophila wing imaginal disc and observed two types of cell motil...

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Detalles Bibliográficos
Autores principales: Shen, Jie, Lu, Juan, Sui, Liyuan, Wang, Dan, Yin, Meizhen, Hoffmann, Inka, Legler, Anne, Pflugfelder, Gert O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322970/
https://www.ncbi.nlm.nih.gov/pubmed/25344916

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