Melanoma-initiating cells exploit M2 macrophage TGFβ and arginase pathway for survival and proliferation

M2 macrophages promote tumor growth and metastasis, but their interactions with specific tumor cell populations are poorly characterized. Using a mouse model of spontaneous melanoma, we showed that CD34(−) but not CD34(+) tumor-initiating cells (TICs) depend on M2 macrophages for survival and prolif...

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Detalles Bibliográficos
Autores principales: Tham, Muly, Tan, Kar Wai, Keeble, Jo, Wang, Xiaojie, Hubert, Sandra, Barron, Luke, Tan, Nguan Soon, Kato, Masashi, Prevost-Blondel, Armelle, Angeli, Veronique, Abastado, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322977/
https://www.ncbi.nlm.nih.gov/pubmed/25294815

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