NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma

We reported previously that increased expression of aldehyde dehydrogenase 1 (ALDH1) in multiple myeloma (MM) is a marker of tumor-initiating cells (TICs) that is further associated with chromosomal instability (CIN). Here we demonstrate that member A1 of the ALDH1 family of proteins, ALDH1A1, is mo...

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Detalles Bibliográficos
Autores principales: Yang, Ye, Zhou, Wen, Xia, Jiliang, Gu, Zhimin, Wendlandt, Erik, Zhan, Xin, Janz, Siegfried, Tricot, Guido, Zhan, Fenghuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322982/
https://www.ncbi.nlm.nih.gov/pubmed/25230277

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