MBL-II-141, a chromone derivative, enhances irinotecan (CPT-11) anticancer efficiency in ABCG2-positive xenografts

ABCG2 is responsible for the multidrug resistance (MDR) phenotype, and strongly modulates cancer outcomes. Its high expression at a number of physiological barriers, including blood-brain and intestinal barriers, impacts on drug pharmacokinetics parameters. We characterized MBL-II-141, a specific an...

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Detalles Bibliográficos
Autores principales: Honorat, Mylène, Guitton, Jérôme, Gauthier, Charlotte, Bouard, Charlotte, Lecerf-Schmidt, Florine, Peres, Basile, Terreux, Raphaël, Gervot, Héloïse, Rioufol, Catherine, Boumendjel, Ahcène, Puisieux, Alain, Di Pietro, Attilio, Payen, Léa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323000/
https://www.ncbi.nlm.nih.gov/pubmed/25474134

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